Assembling Amperometric Biosensors for Clinical Diagnostics

Assembling Amperometric Biosensors for Clinical Diagnostics

Clinical diagnosis and disease prevention routinely require the assessment ofspecies determined by chemical analysis. Biosensor technology offers several benefits overconventional diagnostic analysis. They include simplicity of use, specificity for the targetanalyte, speed to arise to a result, capability for continuous monitoring and multiplexing,together with the potentiality of coupling to l...

Amperometric Biosensors for Lactate, Alcohols and Glycerol Assays in Clinical Diagnostics

ZnO-Based Amperometric Enzyme Biosensors

Nanostructured ZnO with its unique properties could provide a suitable microenvironment for immobilization of enzymes while retaining their biological activity, and thus lead to an expanded use of this nanomaterial for the construction of electrochemical biosensors with enhanced analytical performance. ZnO-based enzyme electrochemical biosensors are summarized in several tables for an easy over...

Amperometric Tyrosinase Based Biosensors for Serotonin Detection

An amperometric biosensor for serotonin detection and quantification, using a carbon paste electrode modified with cobalt(II) phthalocyanine and tyrosinase is described. The tyrosinase immobilization on carbon nanopowder was made using drop-and-dry method followed by cross-linking with glutaraldehyde. The novel biosensor response was optimized using serotonin and it presented the best performan...

Saliva-Based Biosensors: Noninvasive Monitoring Tool for Clinical Diagnostics

Saliva is increasingly recognised as an attractive diagnostic fluid. The presence of various disease signalling salivary biomarkers that accurately reflect normal and disease states in humans and the sampling benefits compared to blood sampling are some of the reasons for this recognition. This explains the burgeoning research field in assay developments and technological advancements for the d...